Recombinant D. melanogaster Protein spaetzle(spz)

Drosophila melanogaster

spz

spz; CG6134; Protein spaetzle [Cleaved into: Protein spaetzle C-106]

26-326

[Isoform 8.19]: Secreted. Note=Secreted in a cell culture system; [Isoform 8.29]: Secreted. Note=Secreted in a cell culture system; [Isoform 11.15]: Secreted. Note=Secreted in a cell culture system; [Isoform 11.6]: Secreted. Note=Secreted in a cell culture system; [Isoform 11.7]: Secreted. Note=Secreted in a cell culture system.

The activated form, spaetzle C-106, acts as a ligand for the Toll receptor. Binding to Toll activates the Toll signaling pathway and induces expression of the antifungal peptide drosomycin. Component of the extracellular signaling pathway that establishes dorsal-ventral polarity in the embryo.

KEGG: Dmel_CG6134; STRING: 7227.FBpp0084507; UniGene: Dm.3462

Recombinant Protein

Yeast; E. coli; Baculovirus; Mammalian cell

KEYER IIKELFTITN DEGVVLFNTS ADSAPFMPIP TQHDDPTQKQ KQNQNQSPIP ETNRHYHQYH SLIQPDQYFK VQRSPNGKLN LVFNDTFVSL QRTDTEVQSE QPIPPRHPSD TFVFPDSPIA KYRPPQSPAR PLRNDTKEHN PCAKDESQHL RNFCTNVDDY PDLSGLTHKL KNNFAKFFSN DLQPTDVSSR VGGSDERFLC RSIRKLVYPK KGLRADDTWQ LIVNNDEYKQ AIQIEECEGA DQPCDFAANF PQSYNPICKQ HYTQQTLASI KSDGELDVVQ NSFKIPSCCK CALKTG

Full Length of Mature Protein

>85% (SDS-PAGE)

The following tags are available. N-terminal His-tagged Tag-Free

Lyophilized powder

Tris/PBS-based buffer, 6% Trehalose, pH 8.0

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Delivery time may differ from different purchasing ways or locations, please kindly consult us for specific delivery times.

Store at -20 °C/-80 °C upon receipt, aliquoting is necessary for multiple use.

The shelf life is related to many factors, including storage state, buffer ingredients, storage temperature, and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C.

Repeated freezing and thawing are not recommended.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Store working aliquots at 4 °C for up to one week.