Recombinant D. melanogaster Histone H4(His4)
- Catalog Number: CDRPO-3110408
- Size: 20 μg; 100 μg; 1000 μg
Target Information
| Species | Drosophila melanogaster |
| Target Names | His4 |
| Alternative Names | His4; H4; His4r; H4r; CG3379; His4:CG31611; CG31611; His4:CG33869; CG33869; His4:CG33871; CG33871; His4:CG33873; CG33873; His4:CG33875; CG33875; His4:CG33877; CG33877; His4:CG33879; CG33879; His4:CG33881; CG33881; His4:CG33883; CG33883; His4:CG33885; CG33885; His4:CG33887; CG33887; His4:CG33889; CG33889; His4:CG33891; CG33891; His4:CG33893; CG33893; His4:CG33895; CG33895; His4:CG33897; CG33897; His4:CG33899; CG33899; His4:CG33901; CG33901; His4:CG33903; CG33903; His4:CG33905; CG33905; His4:CG33907; CG33907; His4:CG33909; CG33909; Histone H4 |
| Expression Region | 2-103 |
| Subcellular Location | Nucleus. Chromosome. |
| Protein Families | Histone H4 family |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Database Info | KEGG: Dmel_CG31611; STRING: 7227.FBpp0091154; UniGene: Dm.29514 |
Product Details
| Product Type | Recombinant Protein |
| Source | Yeast; E. coli; Baculovirus; Mammalian cell |
| Target Protein Sequence | TGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK VFLENVIRDA VTYTEHAKRK TVTAMDVVYA LKRQGRTLYG FGG |
| Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged Tag-Free |
| Form | Lyophilized powder |
| Buffer before Lyophilization | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
| Lead Time | Delivery time may differ from different purchasing ways or locations, please kindly consult us for specific delivery times. |
Storage & Handling
| Storage Condition | Store at -20 °C/-80 °C upon receipt, aliquoting is necessary for multiple use. |
| Shelf Life | The shelf life is related to many factors, including storage state, buffer ingredients, storage temperature, and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. |
| Handling | Repeated freezing and thawing are not recommended. |
| Limitations | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Store working aliquots at 4 °C for up to one week. |
For research use only. Not intended for any clinical use.