Recombinant D. melanogaster Histone H2B(His2B)
- Catalog Number: CDRPO-3110406
- Size: 20 μg; 100 μg; 1000 μg
Target Information
Species | Drosophila melanogaster |
Target Names | His2B; |
Alternative Names | His2B; His2B:CG17949; CG17949; His2B:CG33868; CG33868; His2B:CG33870; CG33870; His2B:CG33872; CG33872; His2B:CG33874; CG33874; His2B:CG33876; CG33876; His2B:CG33878; CG33878; His2B:CG33880; CG33880; His2B:CG33882; CG33882; His2B:CG33884; CG33884; His2B:CG33886; CG33886; His2B:CG33888; CG33888; His2B:CG33890; CG33890; His2B:CG33892; CG33892; His2B:CG33894; CG33894; His2B:CG33896; CG33896; His2B:CG33898; CG33898; His2B:CG33900; CG33900; His2B:CG33902; CG33902; His2B:CG33904; CG33904; His2B:CG33906; CG33906; His2B:CG33908; CG33908; His2B:CG33910; CG33910; Histone H2B |
Expression Region | 2-123 |
Subcellular Location | Nucleus. Chromosome. |
Protein Families | Histone H2B family |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Database Info | KEGG: Dmel_CG17949; STRING: 7227.FBpp0091155 |
Product Details
Product Type | Recombinant Protein |
Source | Yeast; E. coli; Baculovirus; Mammalian cell |
Target Protein Sequence | PPKTSGKAA KKAGKAQKNI TKTDKKKKRK RKESYAIYIY KVLKQVHPDT GISSKAMSIM NSFVNDIFER IAAEASRLAH YNKRSTITSR EIQTAVRLLL PGELAKHAVS EGTKAVTKYT SSK |
Protein Length | Full Length of Mature Protein |
Purity | >85% (SDS-PAGE) |
Tag Info | The following tags are available. N-terminal His-tagged Tag-Free |
Form | Lyophilized powder |
Buffer before Lyophilization | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Lead Time | Delivery time may differ from different purchasing ways or locations, please kindly consult us for specific delivery times. |
Storage & Handling
Storage Condition | Store at -20 °C/-80 °C upon receipt, aliquoting is necessary for multiple use. |
Shelf Life | The shelf life is related to many factors, including storage state, buffer ingredients, storage temperature, and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. |
Handling | Repeated freezing and thawing are not recommended. |
Limitations | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Store working aliquots at 4 °C for up to one week. |
For research use only. Not intended for any clinical use.