Recombinant D. melanogaster Chromodomain-helicase-DNA-binding protein Mi-2 homolog(Mi-2), partial
- Catalog Number: CDRPO-3110539
- Size: 20 μg; 100 μg; 1000 μg
Target Information
| Species | Drosophila melanogaster |
| Target Names | Mi-2 |
| Alternative Names | Mi-2; CG8103; EC 3.6.4.12; ATP-dependent helicase Mi-2; dMi-2 |
| Subcellular Location | Nucleus. Chromosome. |
| Protein Families | SNF2/RAD54 helicase family |
| Function | Helicase which acts in nucleosome-remodeling by catalyzing ATP-dependent nucleosome mobilization. Involved in regulating transcription. Plays a vital role in development. Binds to a portion of Hunchback (HB) protein that is critical for repression of bithorax complex (BXC) genes. May also function in polycomb group (PcG) repression of Hox genes. May also act as part of the nucleosome remodeling and deacetylase complex (the NuRD complex) which participates in the remodeling of chromatin by deacetylating histones. |
| Database Info | KEGG: Dmel_CG8103; STRING: 7227.FBpp0099808; UniGene: Dm.28317 |
Product Details
| Product Type | Recombinant Protein |
| Source | Yeast; E. coli; Baculovirus; Mammalian cell |
| Protein Length | Partial |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged Tag-Free |
| Form | Lyophilized powder |
| Buffer before Lyophilization | Tris/PBS-based buffer, 6% Trehalose, pH 8.0 |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 °C/-80 °C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
| Lead Time | Delivery time may differ from different purchasing ways or locations, please kindly consult us for specific delivery times. |
Storage & Handling
| Storage Condition | Store at -20 °C/-80 °C upon receipt, aliquoting is necessary for multiple use. |
| Shelf Life | The shelf life is related to many factors, including storage state, buffer ingredients, storage temperature, and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 °C/-80 °C. The shelf life of lyophilized form is 12 months at -20 °C/-80 °C. |
| Handling | Repeated freezing and thawing are not recommended. |
| Limitations | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Store working aliquots at 4 °C for up to one week. |
For research use only. Not intended for any clinical use.