Drosophila Growth Phenotypes Assay
Growth refers to both the growth of cells and tissues as well as the differentiation and functional refinement of cells. Drosophila has become a popular model system for studying biological growth. Using the Drosophila model, many factors have been found to influence life trajectories, such as nutritional intake, oxidative stress, sleep, etc. Drosophila being a fully metamorphic developing insect, accurate identification and quantification of growth and developmental phenotypes is crucial for the outcome and analysis of the entire experiment. However, these phenotypes are susceptible to environmental and manipulative influences that can easily lead to biased results or difficulties in detecting major genotypes.
CD BioSciences is committed to a strategy of high-throughput (>500 flies) detection of Drosophila growth and developmental phenotypes for pre-discovery of linked phenotypes and post validation. We have established a standard Drosophila rearing laboratory with strict controls on age and nutritional effects. Combined with our Drosophila genetic foundation service, we can better establish the linkage between genotype and phenotype to help your drug discovery and disease association genes. Our photo platform provides you with high resolution phenotype images.
Fig.1 The life cycle of D. melanogaster (Flatt et al, 2020)
Our Service
There are so many phenotypes of growth and development that we offer a holistic analysis solution from strategy design, standardized (or condition-limited) breeding, data collection, and statistical analysis. All you need to do is tell us of your project details and research objectives, and we will assemble a dedicated project team to help you obtain high-quality results quickly.
If you would like to assay your own samples, please mail them to us 2 months prior to the start of the project, as we require parasite, virus, Wolbachia and viability testing prior to stocking.
| Service | Descriptions |
|---|---|
| Larval Weight | To examine the effects of chemicals, microbes, etc., or genetic mutations on feeding. |
| Life Span | Drosophila has four insect states: embryo, larva (three stages), pupa and adult, and the timing and status of the developmental stages are important indicators for assessing growth, developmental quality and speed Used to evaluate drugs, pathological genes, aging, etc. |
| Fecundity | Reproduction is an important function that affects the continuation of the population. For the assessment of aging, developmental degree and other indicators. |
| Wing Size and Type | To assess the size of the whole body, and the wing type development. |
| Survival | To assess damage from starvation, radiation, infection, etc. |
Why CD BioSciences?
- Rich experience in growth phenotypes assay
- Excellent and professional research team and technical platform
- Flexible Drosophila assay and customized statistical analysis services
- Reliable experimental data with good repeatability
- Fast turnaround, cost-effective and transparent pricing
CD BioSciences is an expert in fruit fly field. We provide professional solutions for Drosophila growth and development phenotypes. Our team of professionals provides 24 × 7 customer service to every client for saving time and effort. There are no limitations of our service. If you need any further information or have any question, please feel free to contact us.
Reference
- Flatt T. (2020). Life-history evolution and the genetics of fitness components in Drosophila melanogaster. Genetics. 214(1), 3-48.
For research use only. Not intended for any clinical use.
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