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Drosophila Circadian Rhythm and Sleep Analysis Service

Drosophila melanogaster, commonly known as the fruit fly, has been a valuable model organism in circadian rhythm and sleep research, providing critical insights into various biological processes. At CD BioSciences, we are passionate about advancing scientific research, and our specialized Drosophila circadian rhythm and sleep analysis service is designed to cater to the specific needs of researchers in this field.

Introduction to Drosophila Circadian Rhythm and Sleep

Drosophila serves as valuable model organisms for studying circadian rhythms and sleep. Their internal clocks are governed by conserved clock genes and neuronal circuits, enabling researchers to investigate the underlying mechanisms. The fly's 24-hour sleep-wake cycle closely resembles that of mammals, making it an ideal system to explore the regulation of sleep. Studies in Drosophila have provided crucial insights into the molecular basis of circadian rhythms and sleep, offering valuable implications for understanding human sleep disorders and optimizing health and performance.

Evaluation of the relationship between PD and circadian clock alterations using D. melanogaster.

Fig.1 Evaluation of the relationship between PD and circadian clock alterations using D. melanogaster. (De Lazzari F., et al. 2018)

Drosophila circadian rhythm and sleep analysis involve studying the biological clock and sleep patterns in Drosophila. Researchers use a variety of techniques, including monitoring locomotor activity in response to light-dark cycles, constant darkness, or temperature changes. They study key genes involved in circadian regulation and employ methods like electroencephalography (EEG) and electromyography (EMG) to analyze sleep-wake patterns. By understanding the molecular basis of circadian rhythms and sleep in Drosophila, scientists gain valuable insights into the fundamental mechanisms underlying these processes.

Our Services

Our Drosophila circadian rhythm and sleep analysis service is designed to cater to the specific needs of researchers studying circadian biology, sleep-wake cycles, and related phenomena in Drosophila melanogaster. Our team of expert researchers will assist you in interpreting the collected data, identifying significant trends, and performing statistical analyses. CD BioSciences specific services include, but are not limited to:

  • Period Length Measurement: We measure the length of the circadian rhythm period to understand the intrinsic clock timing of Drosophila under various conditions.
  • Phase Shifts Measurement: By subjecting Drosophila to controlled light-dark transitions, we analyze phase shifts in their circadian rhythms, shedding light on the mechanisms behind synchronization.
  • Sleep Patterns Measurement: Through activity monitoring, we quantify sleep patterns, including sleep onset, sleep duration, and fragmentation, revealing the dynamics of Drosophila sleep.

Want to Learn More?

At CD BioSciences, we specialize in providing cutting-edge services in the field of Drosophila research. Whether you are an academic researcher, pharmaceutical company, or biotech firm, our Drosophila circadian rhythm and sleep analysis service offers you a reliable and efficient solution for your research needs. With our service, you can save time and resources while obtaining high-quality data, accelerating your research progress, and contributing to the broader scientific community's knowledge. Contact us to learn more about our service and discuss how we can assist you in your Drosophila research endeavors.

References

  • Dubowy C, Sehgal A. Circadian rhythms and sleep in Drosophila melanogaster. Genetics, 2017, 205(4): 1373-1397.
  • Tataroglu O, Emery P. Studying circadian rhythms in Drosophila melanogaster. Methods, 2014, 68(1): 140-150.
  • De Lazzari F, Bisaglia M, Zordan M A, et al. Circadian rhythm abnormalities in Parkinson's disease from humans to flies and back. International Journal of Molecular Sciences, 2018, 19(12): 3911.

For research use only. Not intended for any clinical use.

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