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Anti-D. melanogaster PolA1 Polyclonal Antibody

  • Catalog Number:  CDDMAB-3120127
  • Size:  100 μL; 50 μL; More Options

Target Information

Target Names

PolA1

Gene ID

42553

Function

Catalytic subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit PolA1, an accessory subunit PolA2 and two primase subunits, the catalytic subunit Prim1 and the regulatory subunit Prim2) is recruited to DNA at the replicative forks. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively. In addition to polymerase activity, exhibits 3' to 5' exonuclease activity.

Product Details

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugate

Non-conjugated

Purification Method

Protein A or G purified

Immunogen

Recombinant Drosophila melanogaster PolA1 protein.

Form

Liquid

Buffer

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Concentration

It differs from different batches. Please contact us to confirm it.

Usage

Applications

ELISA, WB

Species Reactivity

Drosophila melanogaster

Storage & Handling

Storage Temp.

Store at -20 °C or -80 °C.

Handling

Avoid freeze-thaw cycles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

For research use only. Not intended for any clinical use.