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Anti-D. melanogaster mt:CoI Polyclonal Antibody

  • Catalog Number:  CDDMAB-3120257
  • Size:  100 μL; 50 μL; More Options

Target Information

Target Names

mt:CoI

Gene ID

19893533

Function

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

Product Details

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugate

Non-conjugated

Purification Method

Protein A or G purified

Immunogen

Recombinant Drosophila melanogaster mt:CoI protein.

Form

Liquid

Buffer

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Concentration

It differs from different batches. Please contact us to confirm it.

Usage

Applications

ELISA, WB

Species Reactivity

Drosophila melanogaster

Storage & Handling

Storage Temp.

Store at -20 °C or -80 °C.

Handling

Avoid freeze-thaw cycles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

For research use only. Not intended for any clinical use.