Anti-D. melanogaster GABARAP Polyclonal Antibody - BSA Free
- Catalog Number: CDDMAB-3120453
- Size: 100 μL; 50 μL; More Options
Target Information
Target Names | GABARAP |
Function | In several neurological diseases, GABARAP expression is related to autophagic functions. In Lewy body disease and Parkinson's disease, LC3 and GABARAP are often co-localized. Autophagy is regulated both at the transcriptional and post-transcriptional level, partially by the activation of GABARAP and other core autophagy machinery proteins. Although autophagy is usually considered to be important in cellular maintenance, and breakdown of proteins and organelles in cell death, it is becoming more and more clear that it plays an important role in the developmental process, including embryogenesis. This embryological effect seems to be partly regulated by GABARAP expression and activity. |
Product Details
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Conjugate | Non-conjugated |
Purification Method | Immunogen affinity purified |
Immunogen | A synthetic peptide made to a C-terminal region of the human GABARAP protein (within residues 50-117). |
Form | Liquid |
Buffer | PBS, 30% Glycerol |
Concentration | 1.11 mg/mL |
Usage
Applications | WB, ICC/IF, IHC, IHC-P |
Species Reactivity | Drosophila melanogaster |
Storage & Handling
Storage Temp. | Store at -20 °C or -80 °C. |
Handling | Avoid freeze-thaw cycles. |
Limitations | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt. |
For research use only. Not intended for any clinical use.