Anti-D. melanogaster FAT1 Monoclonal Antibody
- Catalog Number: CDDMAB-3120959
- Size: 100 μL; 50 μL; More Options
Target Information
| Target Names | FAT1 |
| Function | The Drosophila FAT 1 gene does not belong to the classical cadherin gene family yet encodes a transmembrane protein containing 34 cadherin repeats in association with a number of other motifs. The Drosophila FAT locus encodes a tumor suppressor gene and recessive (loss-of-function) mutations lead to hyperplastic overgrowth of the imaginal discs, indicating that contact dependent cell interactions may play an important role in regulating growth and cell adhesion. This excessive cell proliferation occurs while maintaining normal epithelial organization and differentiation potential. Expressed in many epithelial and some endothelial and smooth muscle cells. Humans contain many homologs of FAT including FAT1, or hFAT |
Product Details
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgM |
| Conjugate | Non-conjugated |
| Purification Method | Thiophilic Chromatography |
| Immunogen | Cytoplasmic domain of Drosophila melanogaster Fat. |
| Form | Liquid |
| Buffer | PBS, pH 7.4 |
| Concentration | 1 mg/mL |
Usage
| Applications | WB, ELISA, ICC/IF, IHC |
| Species Reactivity | Drosophila melanogaster |
Storage & Handling
| Storage Temp. | Store at -20 °C or -80 °C. |
| Handling | Avoid freeze-thaw cycles. |
| Limitations | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt. |
For research use only. Not intended for any clinical use.