Anti-D. melanogaster CycG Polyclonal Antibody

CycG

43724

Cyclin with roles in multiple processes including transcription, meiotic recombination repair, cell cycle regulation, and promotion of normal growth and metabolism. Binds to the promoter region of the homeobox gene Abd-B and is involved in maintaining Abd-B expression in the pupal epithelium. Involved in the transcriptional repression of the homeotic genes Scr and Ubx. Plays a role in meiotic recombination repair of DNA double-strand breaks which ensures efficient translation of grk and promotes grk activity in the oocyte, leading to oocyte dorso-ventral axis formation following secretion of grk from the oocyte and its binding to Egfr in the directly overlying follicle cells. Negatively regulates the binding of serine/threonine-protein kinase Akt1 to the protein phosphatase 2A subunit wdb, promoting normal growth and metabolism. Required for the formation of bilateral symmetry. Negatively regulates cell cycle progression by preventing G1 to S transition and retarding S-phase progression.

Rabbit

Polyclonal

IgG

Non-conjugated

Protein A or G purified

Recombinant Drosophila melanogaster CycG protein.

Liquid

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

It differs from different batches. Please contact us to confirm it.

ELISA, WB

Drosophila melanogaster

Store at -20 °C or -80 °C.

Avoid freeze-thaw cycles.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.