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Anti-D. melanogaster CycC Polyclonal Antibody

  • Catalog Number:  CDDMAB-3120276
  • Size:  100 μL; 50 μL; More Options

Target Information

Target Names

CycC

Gene ID

41801

Function

Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase Cdk8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. Required for leg and eye development and macrochaete specification or differentiation.

Product Details

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugate

Non-conjugated

Purification Method

Protein A or G purified

Immunogen

Recombinant Drosophila melanogaster CycC protein.

Form

Liquid

Buffer

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Concentration

It differs from different batches. Please contact us to confirm it.

Usage

Applications

ELISA, WB

Species Reactivity

Drosophila melanogaster

Storage & Handling

Storage Temp.

Store at -20 °C or -80 °C.

Handling

Avoid freeze-thaw cycles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

For research use only. Not intended for any clinical use.