Anti-D. melanogaster Clk Polyclonal Antibody
- Catalog Number: CDDMAB-3120219
- Size: 100 μL; 50 μL; More Options
Target Information
Target Names | Clk |
Gene ID | |
Function | Circadian regulator that acts as a transcription factor and generates a rhythmic output with a period of about 24 hours. Oscillates in antiphase to the cycling observed for period (PER) and timeless (TIM). According to PubMed:9742131, reaches peak abundance within several hours of the dark-light transition at ZT0 (zeitgeber 0), whereas PubMed:9616122 describes bimodal oscillating expression with maximum at ZT5 and ZT23. Clock-cycle heterodimers activate cycling transcription of PER and TIM by binding to the E-box (5'-CACGTG-3') present in their promoters. Once induced, Period and Timeless block Clock's ability to transactivate their promoters. |
Product Details
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Conjugate | Non-conjugated |
Purification Method | Protein A or G purified |
Immunogen | Recombinant Drosophila melanogaster Clk protein. |
Form | Liquid |
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Concentration | It differs from different batches. Please contact us to confirm it. |
Usage
Applications | ELISA, WB |
Species Reactivity | Drosophila melanogaster |
Storage & Handling
Storage Temp. | Store at -20 °C or -80 °C. |
Handling | Avoid freeze-thaw cycles. |
Limitations | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt. |
For research use only. Not intended for any clinical use.