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Anti-D. melanogaster Bre1 Polyclonal Antibody

  • Catalog Number:  CDDMAB-3120330
  • Size:  100 μL; 50 μL; More Options

Target Information

Target Names

Bre1

Gene ID

38652

Function

E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-117' of histone H2B. H2B 'Lys-117' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It thereby plays a central role in histone code and gene regulation. Required for the expression of Notch target genes in development by affecting the levels of Su(H) in imaginal disk cells and stimulating the Su(H)-mediated transcription of Notch-specific genes.

Product Details

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugate

Non-conjugated

Purification Method

Protein A or G purified

Immunogen

Recombinant Drosophila melanogaster Bre1 protein.

Form

Liquid

Buffer

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Concentration

It differs from different batches. Please contact us to confirm it.

Usage

Applications

ELISA, WB

Species Reactivity

Drosophila melanogaster

Storage & Handling

Storage Temp.

Store at -20 °C or -80 °C.

Handling

Avoid freeze-thaw cycles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

For research use only. Not intended for any clinical use.