about-banner

Anti-D. melanogaster Akt1 Polyclonal Antibody

  • Catalog Number:  CDDMAB-3120920
  • Size:  100 μL; 50 μL; More Options

Target Information

Target Names

Akt1

Gene ID

41957

Function

Serine/threonine kinase involved in various developmental processes. During early embryogenesis, acts as a survival protein. During mid-embryogenesis, phosphorylates and activates trh, a transcription factor required for tracheal cell fate determination. Also regulates tracheal cell migration. Later in development, acts downstream of PI3K and Pk61C/PDK1 in the insulin receptor transduction pathway which regulates cell growth and organ size, by phosphorylating and antagonizing FOXO transcription factor. Controls follicle cell size during oogenesis. May also stimulate cell growth by phosphorylating Gig/Tsc2 and inactivating the Tsc complex. Dephosphorylation of 'Ser-586' by Phlpp triggers apoptosis and suppression of tumor growth.

Product Details

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugate

Non-conjugated

Purification Method

Protein A or G purified

Immunogen

Recombinant Drosophila melanogaster Akt1 protein.

Form

Liquid

Buffer

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Concentration

It differs from different batches. Please contact us to confirm it.

Usage

Applications

ELISA, WB

Species Reactivity

Drosophila melanogaster

Storage & Handling

Storage Temp.

Store at -20 °C or -80 °C.

Handling

Avoid freeze-thaw cycles.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

For research use only. Not intended for any clinical use.